x

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.

Attention

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Noonan syndrome with multiple lentigines

Disease definition

A rare multisystem genetic disorder characterized by lentigines, hypertrophic cardiomyopathy, short stature, pectus deformity, and dysmorphic facial features.

ORPHA:500

Classification level: Disorder
  • Synonym(s):
    • Cardiomyopathic lentiginosis
    • Familial multiple lentigines syndrome
    • LEOPARD syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant 
  • Age of onset: Childhood
  • ICD-10: Q87.1
  • OMIM: 151100  611554  613707
  • UMLS: C0175704  C2931424
  • MeSH: C537116  D044542
  • GARD: 1100
  • MedDRA: 10062901

Detailed information

Article for general public

Professionals

Additional information

Further information on this disease

Health care resources for this disease

Research activities on this disease

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.