Orphanet: HANAC syndrome

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HANAC syndrome

Disease definition

A rare multisystemic disease characterized by small-vessel brain disease, cerebral aneurysm, and extracerebral findings involving the kidney, muscle, and small vessels of the eye.


Classification level: Disorder
  • Synonym(s):
    • Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome
    • Hereditary angiopathy-nephropathy-aneurysms-muscle cramps syndrome
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Childhood
  • ICD-10: I99
  • OMIM: 611773
  • UMLS: C2673195
  • MeSH: -
  • GARD: 10889
  • MedDRA: -

Detailed information


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