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Acquired idiopathic sideroblastic anemia

Disease definition

Acquired idiopathic sideroblastic anaemia is one of a group of disorders known as the myelodysplastic syndromes (MDS) characterised by ineffective haemopoiesis affecting one or more blood cell lineages (myeloid, erythroid or megakaryocytic) leading to peripheral blood cytopenias and an increased risk of developing leukaemia. Acquired idiopathic sideroblastic anaemia is now more commonly referred to as refractory anaemia with ringed sideroblasts or the acronym RARS.

ORPHA:75564

  • Synonym(s):
    • AISA
    • Primary acquired sideroblastic anemia
    • RARS
    • Refractory anemia with ringed sideroblasts
  • Prevalence: 1-9 / 100 000
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: D64.3
  • OMIM: -
  • UMLS: C1264195
  • MeSH: -
  • GARD: 8249
  • MedDRA: -

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