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Thyrotoxic periodic paralysis

Disease definition

Thyrotoxic periodic paralysis (TPP) is a rare neurological disease characterized by recurrent episodes of paralysis and hypokalemia during a thyrotoxic state.


Classification level: Disorder
  • Synonym(s):
    • Thyrotoxic hypokalemic periodic paralysis
  • Prevalence: <1 / 1 000 000
  • Inheritance: Multigenic/multifactorial or Not applicable 
  • Age of onset: Adult
  • ICD-10: G72.3
  • OMIM: 188580  613239  614834
  • UMLS: C0268446
  • MeSH: -
  • GARD: 10814
  • MedDRA: 10043788
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