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Steroid-responsive encephalopathy associated with autoimmune thyroiditis

Disease definition

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare, acquired, neurological disease characterized by encephalopathy associated with elevated antithyroid antibodies, in the absence of other causes. Clinical presentation varies from minor cognitive impairment to status epilepticus and coma, and frequently includes seizures, confusion, speech disorder, memory impairment, ataxia and psychiatric manifestations.

ORPHA:83601

  • Synonym(s):
    • Hashimoto encephalitis
    • SREAT
  • Prevalence: <1 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: G04.8
  • OMIM: -
  • UMLS: C0393639
  • MeSH: -
  • GARD: 8570
  • MedDRA: -

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