Orphanet: Shiga toxin associated hemolytic uremic syndrome
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Shiga toxin-associated hemolytic uremic syndrome

Disease definition

Typical hemolytic-uremic syndrome (typical HUS) is a thrombotic microangiopathy characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction that is usually associated with prodromal enteritis caused by Shigella dysentriae type 1 or E. Coli.

ORPHA:90038

Classification level: Subtype of disorder
  • Synonym(s):
    • D+ HUS
    • EHEC-HUS
    • Hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli
    • Hemolytic uremic syndrome with diarrhea
    • STEC-HUS
    • Shiga-like toxin-associated HUS
    • Stx-HUS
    • Typical HUS
    • Typical hemolytic uremic syndrome
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: D58.8
  • OMIM: 235400
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

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