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Acute adrenal insufficiency

Disease definition

A primary adrenal insufficiency caused by a sudden defective production of adrenal steroids (cortisol and aldosterone). It represents an emergency, thus the rapid recognition and prompt therapy are critical for survival even before the diagnosis is made.


Classification level: Disorder
  • Synonym(s):
    • Acute adrenal failure
    • Acute adrenocortical insufficiency
    • Addisonian crisis
    • Adrenal crisis
    • Adrenocortical crisis
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive or X-linked dominant or Not applicable 
  • Age of onset: All ages
  • ICD-10: E27.2
  • OMIM: -
  • UMLS: C0151467
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information


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