Orphanet: Nachtelijke frontaalkwab epilepsie

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Autosomal dominant nocturnal frontal lobe epilepsy

Disease definition

A rare seizure disorder characterized by intermittent dystonia and/or choreoathetoid movements that occur during sleep. The clusters of nocturnal motor seizures are often stereotyped and brief.


Classification level: Disorder
  • Synonym(s):
    • ADNFLE
    • Autosomal dominant sleep-related hypermotor epilepsy
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant 
  • Age of onset: Adult, Childhood, Adolescent
  • ICD-10: -
  • OMIM: 600513  603204  605375  610353  615005
  • UMLS: C3696898
  • MeSH: -
  • GARD: 11918
  • MedDRA: -

Detailed information


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.