Orphanet: Leucodistrofia autosómica dominante de inicio en el adulto

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Adult-onset autosomal dominant leukodystrophy

Disease definition

A rare, slowly progressive neurological disorder involving centralnervous systemdemyelination, leading to autonomic dysfunction, ataxia and mild cognitive impairment.


Classification level: Disorder
  • Synonym(s):
    • ADLD
    • Adult-onset autosomal dominant demyelinating leukodystrophy
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Adult
  • ICD-10: E75.2
  • OMIM: 169500
  • UMLS: C1868512  C3164344
  • MeSH: -
  • GARD: 10587
  • MedDRA: -

Detailed information

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