Orphanet: Diabetes mellitus, neonatal, permanente

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Permanent neonatal diabetes mellitus

Disease definition

Permanent neonatal diabetes mellitus (PNDM) is a monogenic form of neonatal diabetes (NDM, see this term) characterized by persistent hyperglycemia within the first 12 months of life in general, requiring continuous insulin treatment.


Classification level: Disorder
  • Synonym(s):
    • Monogenic diabetes of infancy
    • PNDM
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Autosomal dominant or Autosomal recessive 
  • Age of onset: Antenatal, Neonatal, Infancy
  • ICD-10: P70.2
  • OMIM: 606176  618856  618857  618858
  • UMLS: C1833104
  • MeSH: -
  • GARD: 10457
  • MedDRA: -

Detailed information

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