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Exercise-induced hyperinsulinism

Disease definition

Exercise-induced hyperinsulinism (EIHI) is a form of diazoxide-sensitive diffuse hyperinsulinism (DHI) characterized by episodes of hypoglycemia induced by exercise due to an inappropriate lactate and pyruvate sensitivity in pancreatic beta-cells.


Classification level: Disorder
  • Synonym(s):
    • EIHI
    • Exercise-induced hyperinsulinemic hypoglycemia
    • Hyperinsulinism due to SLC16A1 deficiency
    • Hyperinsulinism due to monocarboxylate transporter 1 deficiency
  • Prevalence: -
  • Inheritance: Autosomal dominant 
  • Age of onset: -
  • ICD-10: E16.1
  • OMIM: 610021
  • UMLS: C1864902
  • MeSH: -
  • GARD: 9932
  • MedDRA: -

Detailed information


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