x

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.

Attention

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Orphanet doesn't provide personalised answers. To get in touch with the Orphanet team, please contact

Information provided in your contribution (including your email address) will be stocked in .CSV files that will be sent as an email to Orphanet's teams. These emails might be conserved in the teams' mailboxes, in our backoffice servers but will not be registered in our databases (for more information see our section General Data Protection Regulation and data privacy (GDPR) and Confidentiality).

Captcha image

Cleft lip/palate

Disease definition

Cleft lip and palate is a fissure type embryopathy extending across the upper lip, nasal base, alveolar ridge and the hard and soft palate.

ORPHA:199306

Classification level: Disorder
  • Synonym(s):
    • Alveolar cleft lip and palate
    • Cleft lip and palate
    • Cleft lip-alveolus-palate syndrome
    • FLP
  • Prevalence: 1-5 / 10 000
  • Inheritance: Multigenic/multifactorial 
  • Age of onset: Infancy, Neonatal
  • ICD-10: Q37.0  Q37.1  Q37.2  Q37.3  Q37.4  Q37.5  Q37.8  Q37.9
  • OMIM: 119530  129400  225060  600625  600757  602966  608371  608864  608874  610361  612858  613705  616788  618149
  • UMLS: C0158646
  • MeSH: -
  • GARD: -
  • MedDRA: 10009260

Detailed information

Professionals

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.