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Adult hepatocellular carcinoma

Disease definition

A rare carcinoma of the liver characterized by one to several or many nodules occurring anywhere within the liver, composed of neoplastic epithelial cells with hepatocellular differentiation. The vast majority of tumors are associated with chronic liver disease (such as hepatitis B or C, or steatohepatitis) or exposure to a variety of exogenous agents. Patients may present with signs and symptoms related to the tumor, as well as to the underlying condition. Common manifestations include right upper quadrant abdominal pain, weight loss, hepatosplenomegaly, jaundice, and ascites. Symptomatic tumors generally have poor prognosis.

ORPHA:210159

Classification level: Disorder
  • Synonym(s):
    • Adult HCC
  • Prevalence: -
  • Inheritance: Not applicable 
  • Age of onset: Adult, Elderly
  • ICD-10: C22.0
  • OMIM: 114550
  • UMLS: -
  • MeSH: -
  • GARD: 6608
  • MedDRA: -

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.