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Solitary median maxillary central incisor syndrome

Disease definition

Solitary median maxillary central incisor syndrome (SMMCI) is a complex disorder consisting of multiple, mainly midline, defects of development resulting from unknown factor(s) operating in utero from about the 35th-38th day after conception.


  • Synonym(s):
    • SMMCI
    • Single upper central incisor
  • Prevalence: Unknown
  • Inheritance: Multigenic/multifactorial 
  • Age of onset: Childhood
  • ICD-10: K00.2
  • OMIM: 147250
  • UMLS: C1840235
  • MeSH: C537342
  • GARD: 4877
  • MedDRA: -

Detailed information


Additional information

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