Orphanet: Isolated focal non epidermolytic palmoplantar keratoderma

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Disease definition

A rare hereditary palmoplantar keratoderma characterized by focal hyperkeratotic lesions on the palms and soles. Histopathologic examination reveals prominent hyperkeratosis, thickened stratum spinosum with reduced stratum granulosum, disadhesion of cells in the suprabasal layers, elongation of rete ridges, and sparse lymphocyte infiltration in the dermis.

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Isolated focal non-epidermolytic palmoplantar keratoderma

ORPHA:448264

A summary on this disease is available in Español (2021) Français (2021) Nederlands (2021)

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