Orphanet: Unverricht Lundborg disease

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Unverricht-Lundborg disease

Disease definition

Unverricht-Lundborg disease (ULD) is a rare progressive myoclonic epilepsy disorder characterized by action- and stimulus-sensitive myoclonus, and tonic-clonic seizures with ataxia, but with only a mild cognitive decline over time.


Classification level: Disorder
  • Synonym(s):
    • PME type 1
    • Progressive myoclonic epilepsy type 1
    • Progressive myoclonus epilepsy type 1
    • ULD
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Autosomal recessive 
  • Age of onset: Childhood, Adolescent
  • ICD-10: G40.3
  • OMIM: 254800  310370  612437
  • UMLS: C0751785
  • MeSH: D020194
  • GARD: 3876
  • MedDRA: 10054895

Detailed information


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.