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Hemorrhagic fever-renal syndrome

Disease definition

Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne potentially severe hemorrhagic disease caused by Old World Hantaviruses characterized by high fever, malaise, headache, myalgia, arthralgia, backache, abdominal pain, oliguria/renal failure and systemic hemorrhagic manifestations.


  • Synonym(s):
    • Hantavirosis
    • Hantavirus fever
  • Prevalence: 1-5 / 10 000
  • Inheritance: -
  • Age of onset: All ages
  • ICD-10: A98.5+  N08.0*
  • OMIM: -
  • UMLS: C0019101  C2930957
  • MeSH: C535630  D006480
  • GARD: -
  • MedDRA: 10023484

Detailed information


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