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Autoimmune lymphoproliferative syndrome

Disease definition

A rare, inherited disorder characterized by non-malignant lymphoproliferation, multilineage cytopenias, and a lifelong increased risk of Hodgkin's and non-Hodgkin's lymphoma.

ORPHA:3261

Classification level: Disorder
  • Synonym(s):
    • ALPS
    • Canale-Smith syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant or Autosomal recessive 
  • Age of onset: All ages
  • ICD-10: D47.9
  • OMIM: 601859  603909  615559
  • UMLS: C1328840
  • MeSH: D056735
  • GARD: 8686
  • MedDRA: 10069521

Detailed information

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.