Orphanet: Systemic mastocytosis

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Systemic mastocytosis

Disease definition

A heterogeneous group of rare, acquired and chronic hematological malignancies related to an abnormal accumulation/proliferation of neoplastic mast cells (MCs) in one or several organs, mainly the bone marrow (BM), associated frequently with skin involvement.


Classification level: Group of disorders
  • Synonym(s): -
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: C96.2
  • OMIM: -
  • UMLS: C0221013
  • MeSH: D034721
  • GARD: 8616
  • MedDRA: 10042949

Detailed information

Article for general public


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