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Entospletinib

   
  • INN (International Nonproprietary Name) : entospletinib
  • Code name : GS-9973
  • Chemical name or description : 6-(1H-Indazol-6-yl)-N-(4-morpholinophenyl)imidazo-[1,2-alpha]pyra zin-8-amine bis-methanesulfonate
  • Type of product : Ingredient/substance
  • Type of production : Synthetic / extractive chemistry
  • Orphan designation : EuropeUSA
    • Orphan designation  - Europe

    • Diseases list
      • Inherited acute myeloid leukemia
      • Acute leukemia of ambiguous lineage
      • Unclassified acute myeloid leukemia
      • Acute myeloid leukemia with t(6;9)(p23;q34)
      • Acute myeloid leukemia with t(9;11)(p22;q23)
      • Acute myeloid leukemia with 11q23 abnormalities
      • Acute myeloid leukemia with NPM1 somatic mutations
      • Acute myeloid leukemia with CEBPA somatic mutations
      • Acute myeloid leukemia with t(8;16)(p11;p13) translocation
      • Acute myeloid leukemia with t(8;21)(q22;q22) translocation
      • Acute myeloid leukaemia with myelodysplasia-related features
      • Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)
      • Acute myeloid leukemia with inv3(q21;q26.2) or t(3;3)(q21;q26.2)
      • Therapy related acute myeloid leukemia and myelodysplastic syndrome
      • Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
    • Detailed information
    • Orphan designation  - USA

    • Diseases list
      • Inherited acute myeloid leukemia
      • Acute leukemia of ambiguous lineage
      • Unclassified acute myeloid leukemia
      • Acute myeloid leukemia with t(6;9)(p23;q34)
      • Acute myeloid leukemia with t(9;11)(p22;q23)
      • Acute myeloid leukemia with 11q23 abnormalities
      • Acute myeloid leukemia with NPM1 somatic mutations
      • Acute myeloid leukemia with CEBPA somatic mutations
      • Acute myeloid leukemia with t(8;16)(p11;p13) translocation
      • Acute myeloid leukemia with t(8;21)(q22;q22) translocation
      • Acute myeloid leukaemia with myelodysplasia-related features
      • Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)
      • Acute myeloid leukemia with inv3(q21;q26.2) or t(3;3)(q21;q26.2)
      • Therapy related acute myeloid leukemia and myelodysplastic syndrome
      • Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
    • Detailed information

Additional information

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