Substance(s)

• Acetylleucine
• Angiotensin (1-7)
• Antisense oligonucleotide targeting exon 73 in the COL7A1 gene
• Autologous genetically modified human dermal fibroblasts
• Autologous skin equivalent graft composed of keratinocytes and fibroblasts genetically corrected by CRISPR/Cas9-mediated excision of mutation-carrying COL7A1 exon 80
• Bevacizumab
• Dexamethasone sodium phosphate encapsulated in human erythrocytes
• Etamsylate
• Ex-vivo-expanded autologous fibroblasts transduced with lentiviral vector containing the COL7A1 gene
• Ex-vivo-expanded autologous keratinocytes transduced with retroviral vector containing the COL7A1 gene
• Expanded Allogeneic Human Dermal Fibroblasts In Hypothermosol(R)-Frs
• Human immunoglobulin G1 constant region-human ectodysplasin-A1 receptor-binding domain fusion protein
• Lonafarnib
• Pravastatin / zoledronic acid
• Raloxifene hydrochloride
• Recombinant human alpha 1 chain homotrimer of type VII collagen
• Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7)
• Recombinant human dyskerin
• Sirolimus
• Skin equivalent graft genetically corrected with a COL7A1-encoding SIN retroviral vector
• Synthetic double-stranded siRNA oligonucleotide directed against the keratin 6a N171K mutation
• Thalidomide
• [5,10,15,20-tetrakis(4-carboxyphenyl)-21H,23H-porphine]manganese(III) chloride
• ex-vivo-expanded autologous human keratinocytes containing epidermal stem cells transduced with a COL17A1-encoding retroviral vector
• ex-vivo-expanded autologous human keratinocytes containing epidermal stem cells transduced with a COL7A1-encoding retroviral vector
• ex-vivo-expanded autologous human keratinocytes containing epidermal stem cells transduced with a LAMB3-encoding retroviral vector
• genetically modified replication-incompetent herpes simplex virus-1 expressing collagen VII

Tradename(s)

• EFFIZINC
• RUBOZINC