Substance(s)

• Allantoin
• Allogeneic adipose-derived adult mesenchymal stem cells contained in a fibrin-based bioengineered dermis
• Allogeneic human dermal fibroblasts
• Allogeneic skin-derived ABCB5-positive mesenchymal stem cells
• Angiotensin (1-7)
• Antisense oligonucleotide targeting exon 73 in the COL7A1 gene
• Autologous genetically modified human dermal fibroblasts
• Autologous skin equivalent graft composed of keratinocytes and fibroblasts genetically corrected by CRISPR/Cas9-mediated excision of mutation-carrying COL7A1 exon 80
• Bilayer engineered skin composed of keratinocytes (patient autologous) and fibroblasts (donor allogeneic) in a plasma matrix
• Diacerein
• Dry extract from Betulae cortex (birch bark)
• Ex-vivo-expanded autologous fibroblasts transduced with lentiviral vector containing the COL7A1 gene
• Ex-vivo-expanded autologous keratinocytes transduced with retroviral vector containing the COL7A1 gene
• Expanded Allogeneic Human Dermal Fibroblasts In Hypothermosol(R)-Frs
• Human dermal fibroblasts cultured on a bioresorbable polyglactin mesh
• Losartan
• Recombinant human alpha 1 chain homotrimer of type VII collagen
• Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7)
• Ribonucleoprotein complex composed of two sgRNA and a Cas9 nuclease targeting the human COL7A1 gene
• Skin equivalent graft genetically corrected with a COL7A1-encoding SIN retroviral vector
• ex-vivo-expanded autologous human keratinocytes containing epidermal stem cells transduced with a COL7A1-encoding retroviral vector