Medicamento(s)

• (-)-B-Elemene
• (1E,4E,6E)-1-(3,5-dimethoxyphenyl)-7-(4-hydroxy-3,5dimethoxyphenyl)hepta-1,4,6-trien-3-one
• (3R,3aS,9R,9aS,9bS)-3-((dimethylamino)methyl)-9-hydroxy-6,9-dimethyl-3,3a,4,5,7,8,9,9a-octahydroazuleno[4,5-b]furan-2(9bH)-one fumarate
• (4'aR,10'bR)-8'-chloro-1-[2-(1H-imidazol-1-yl)ethyl]-5',5'-dimethyl-4'a,10'b-dihydro-2'H,4'H,5'H-spiro[piperidine-4,3'-pyrano[3,2-c][1]benzopyran] diphosphate
• (R)-1-(3,3-difluoro-1-methlypiperidin-4-yl)-8-(6-methoxypyridin-3-yl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
• (R)-5-(2-(2,5-difluorophenyl) pyrrolidin-1-yl)-3-(4-(trifluoromethyl)-1H-pyrazol-1-yl) pyrazolo[1,5-a] pyrimidine
• (R,E)-3-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1-(piperazin-1-yl)prop-2-en-1-on hemi-oxalate
• (S)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide
• (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate
• (S)-perillyl alcohol temozolomide
• (Z)-3-(3-(3,5-bis(trifluorometil)fenil-1H-1,2,4-triazol-1-il)-N'-(pirazin-2-il)acrilhidrazida
• 1,2:5,6-Dianidrogalactitol
• 18-(p-(¹³¹I)-iodophenyl)octadecyl phosphocholine
• 18-(p-[124I]-iodophenyl)octadecyl phosphocholine
• 2,4,6,7,8,9-hexahydro-4-((2-methylphenyl)methyl)-7-(phenylmethyl)imidazo(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-one
• 4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
• 4-[123I] iodo-L-phenylalanine
• 4-[131I]iodo-L-phenylalanine
• 4-[2-(6-metilpiridina-2-il)-5,6-dihidro-4H-pirrolo[1,2-b]pirazol-3-il]-quinolina-6- carboxamida mono-hidratada
• 5,5'-(4-(trifluromethyl)benzylazanediyl)bis(methylene)diquinolin-8-ol
• 5-aminolevulinic acid hydrochloride
• 5-fluoro-4-(7'-fluoro-2'-methylspiro[cyclopentane-1,3'-indol]-5'-yl)-N-(5-(1-methylpiperidin-4-yl)pyridin-2-yl)pyrimidin-2-amine
• 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl)ethyl)-4-pyrimidinecarboxamide
• 64-fluoro-36-methox-27-methyl-5-thia-4,8-diaza-2(4,6)-tieno[3,2-d]pyrimidine-3(3,5)-pyridina-1(2,5)-thiophena-6(1,3)-benzeneacyclononaphan-7-one 5,5-dioxide
• 7-beta-hidroxi-cholesteril-3-beta-oleato
• 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(2-(neopentylamino)ethyl)-9H-purin-6-amine, dihydrochloride salt
• Ac-225 alphavbeta3-IAC
• Adenoviral vector serotype 5 encoding the human interleukin-12 p70 transgene
• Adenovirus delta 24-RGD
• Adenovirus-mediated Herpes Simplex Virus-thymidine kinase gene
• Aglatimagene besadenovec
• Aldoxorubicin
• Allogeneic T cells genetically modified to express anti-B7-H3 chimeric antigen receptor (CAR)
• Alrizomadlin
• Altiratinib
• Anti-Beta1 integrin monoclonal antibody
• Anti-GD2 monoclonal antibody 3F8 humanised
• Anticorpo monoclonal humanizado recombinante contra o recetor do fator de crescimento epidérmico conjugado com maleimidocaproil monometilauristatina F
• Anticorpo monoclonal murino anti-GD2
• Anticorpo monoclonal quimérico anti-GD2
• Autologous CD34+ cell enriched haematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding for human Interferon-alpha2 cDNA (Temferon)
• Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3
• Autologous dendritic cells pulsed with autologous cell lysate
• Autologous glioma tumour cells treated with antisense molecule directed against the insulin-like growth factor type 1 receptor
• Azeliragon
• Bevacizumab
• Biotinylated anti-tenascin monoclonal antibody for use with 90-Yttrium
• Bivalent cytomeglaovirus gB/pp65 enveloped virus-like particles
• Boswellia serrata resin extract
• Canabidiol
• Carmustina
• Carmustine (solution for intratumoral injection)
• Cebtutide
• Chimeric monoclonal antibody to O-acetyl-GD2 antigen
• Cilengitida
• Cloridrato de doxorrubicina encapsulado em lipossomas contendo glutationa peguilada
• Cloridrato de enzastaurina
• Combination of carboplatin and sodium valproate
• Complexo L-cisteína, L-leucil-L-alpha-glutamil-L-alpha-glutamil-L-lisil-L-lisilglicil-L-asparaginil-L-tirosina, L-valil-L-valil-L-threonil-L-alpha-aspartil-L-histidil-S-[1-[(4-carboxiciclohexil)metil]-2,5-dioxo-3-pirrolidinila]-, com sitio de ligação de forte afinidade para hemocianina
• Complexo de proteínas/péptidos gp96 obtido por choque térmico, derivado de tumor autólogo
• Conditionally-replicative CD40L-expressing adenovirus
• Copper (64Cu) chloride
• Cyclin-dependent kinase (CDK) inhibitor
• Células dendríticas autólogas carregadas com ARN de células estaminais de glioma
• Células dendríticas autólogas estimuladas com peptídeos sintéticos antigénicos derivados do tumor (MAGE-1, HER-2, AIM-2, TRP-2, gp100 e interleucina 13 do recetor-alfa)
• Células e lisatos celulares alogénicos e autólogos, irradiados e haptenizados, derivados de glioblastoma
• Dabrafenib Mesylate
• Degrader of Lysine-specific histone demethylase 1A and REST Corepressor 1
• Delta-9-tetrahydrocannabinol and cannabidiol from extracts of the Cannabis sativa L. plant
• Diaziquone
• Dimethylaminomicheliolide Fumarate
• Dinutuximab beta
• Doxorubicin
• Doxorubicin (administered after synthetic double-stranded siRNA oligonucleotide directed against claudin-5 complexed with polyethyleneimine)
• Doxorubicin hydrochloride (drug eluting beads)
• Dronabinol and cannabidiol
• Eflornitina
• Erlotinib hydrochloride
• Expanded, activated methylguanine methyltransferase (MGMT) gene-modified gamma-delta T cells drug resistant immunotherapy
• F18-PARPi
• Florilglutamic acid (18F)
• Flucytosine
• Fluorouracil
• Gadodiamide (liposomal)
• Gadolinium-based intravenously administered nanoparticules
• Gallium maltolate
• Gimatecan
• H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-2Thi-Gly-Leu-Met(O2)-NH2-DOTA-213-bismuth
• H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-2Thi-Gly-Leu-Met(O2)-NH2-DOTA-225-Actinium
• Herpes simplex virus lacking infected cell protein 34.5
• Human interleukin 12 fused with immunoglobulin G4 C-terminal Fc fragment
• Human transferrin conjugated to mutant diphtheria toxin
• Humanised IgG1 monoclonal antibody against the receptor-binding site of human placental growth factor
• Humanised monoclonal antibody against epidermal growth factor receptor
• IL-12-secreting dendritic cells, loaded with autologous tumour lysate
• Iodine (131I) Chlorotoxin
• Iodine (131I) anti-nucleohistone H1 chimeric biotinylated monoclonal antibody
• Iodine (131I) anti-tenascin monoclonal antibody 81C6
• Iodine (131I) iobenguane
• Iodine (131I) murine IgG1 monoclonal antibody against CD276
• Irinotecan hydrochloride (drug eluting beads)
• Leucócitos autólogos expandidos ex-vivo e tratados com 5-aza-2'-desoxicitidina
• Lutetium (177Lu) omburtamab barzuxetan
• MV-NB-02, its bivalent ganglioside vaccine consisting of GD2-lactone and GD3-lactone each covalently conjugated to keyhole hemocyanin
• Marizomib
• N-(4-Methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
• Nimotuzumab
• O-(2-[18F]-fluoroéthyl)-l-tyrosine
• Olaptesed pegol
• Oligonucleotide phosphorothioate (TAAACGTTATAACGTTATGACGTCAT)
• Oligonucleótido monocatenário de ácido nucleico peptídico com 16 bases ligado a um péptido de 7 aminoácidos
• Oncolytic Type 1 Herpes Simplex Virus (HSV-1) Expressing Human Cytokine Interleukin 12 (IL-12) and Fab Fragment of Anti-PD-1 Antibody
• Onfekafusp alfa
• PI3K pathway inhibitor
• Paclitaxel-succinato-Arg-Arg-Leu-Ser-Tyr-Ser-Arg-Arg-Arg-Phe
• Panobinostato
• Perifosina
• Picropodophyllin
• Pritumumab
• Proteína de fusão recombinante composta pela parte extracelular do CD95 fundida com a parte Fc da IgG1 humana
• Proteína-4 morfogenética óssea humana recombinante
• Pseudomonas exotoxin (domains II/III)-Interleukin 13 chimeric protein
• Recombinant fusion protein of circulary-permuted IL-4 and pseudomonas exotoxin A, [IL-4(38-37)-PE38KDEL]
• Recombinant human glutamate oxaloacetate transaminase 1
• Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody (rhIL-7-hyFc)
• Recombinant oncolytic virus based on the backbone of Alphavirus M1
• Regorafenib
• Ribociclib
• Rilpivirine
• Salmonella typhi Ty21a strain transfected with a plasmid vector encoding the human vascular endothelial growth factor receptor 2
• Selective rapidly accelerated fibrosarcoma (RAF) murine sarcoma viral oncogene homolog B1 (BRAF) inhibitor
• Small molecule inhibitor of PRMT5 (protein arginine methyl transferase 5)
• Sodium 4-amino-3- [6-( 4-fluoro-2-methylphenyl)pyridine-3-ylazo] naphthalene-1-sulfonate dihydrate
• Synthetic double-stranded siRNA oligonucleotide directed against claudin-5 complexed with polyethyleneimine (prior to administration of doxorubicin)
• Talampanel
• Technetium (99mTc) tetrofosmin
• Temozolomida
• Topotecan hydrochloride (liposomal)
• Trabedersen
• Tranilast
• Veledimex
• Vetor viral adeno-associado contendo o gene Faz-C humano
• Vocimagene amiretrorepvec
• Vorasidenib hemicitrate hemihydrate
• [4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-8-[(1-methyl-4-piperidyl)oxy]-2,3-dihydro-1,4-benzoxazepin-5-one]
• [a-N-(2'succinyl-paclitaxel)Thr]-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Arg-Asn-Asn-Phe-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Thr-Glu-Glu-Tyr
• a tumor lysate-pulsed dendritic cell vaccine, enhanced by addition of a TLR 2, 4, 9 ligand adjuvant cocktail (Pam3cys, LPS, CpG ODN)
• entrectinib
• fluciclovine (18F)
• sodium 2-hydroxylinoleate
• trametinib dimethyl sulfoxide
• Ácido 2-hidroxioleico
• Ácido zoledrónico

Nome(s) de comercialização

• AVASTIN
• BICNU
• CARMUSTINE OBVIUS
• DANYELZA
• GLEOLAN
• GLIADEL
• GLIOLAN
• MEKINIST
• Phelinun
• QARZIBA (previously Dinutuximab beta Apeiron)
• TAFINLAR
• TEMODAL
• TEMODAR
• UNITUXIN