Orphanet: Cold induced sweating syndrome

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Cold-induced sweating syndrome

Disease definition

Cold-induced sweating syndrome (CISS) is characterized by profuse sweating (involving the chest, face, arms and trunk) induced by cold ambient temperature.


Classification level: Disorder
  • Synonym(s):
    • CISS
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal recessive 
  • Age of onset: Childhood, Adult
  • ICD-10: G90.8
  • OMIM: 272430  610313  617055
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information


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