Orphanet: Legg Calvé Perthes disease

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Legg-Calvé-Perthes disease

Disease definition

A rare disorder characterized by uni- or bilateral avascular necrosis (AVN) of the femoral head in children.


Classification level: Disorder
  • Synonym(s):
    • Aseptic necrosis of the capital femoral epiphysis
    • Osteochondrosis of the capital femoral epiphysis
    • Perthes disease
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant or Multigenic/multifactorial 
  • Age of onset: Childhood
  • ICD-10: M91.1
  • OMIM: 150600
  • UMLS: C0023234
  • MeSH: -
  • GARD: 6874
  • MedDRA: 10034735
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