Orphanet: Neu Laxova syndrome

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Neu-Laxova syndrome

Disease definition

Neu-Laxova syndrome (NLS) is a rare, multiple malformation syndrome characterised by severe intrauterine growth retardation (IUGR), severe microcephaly with a sloping forehead, severe ichthyosis (collodion baby type), and facial dysmorphism.


Classification level: Disorder
  • Synonym(s): -
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal recessive 
  • Age of onset: Antenatal
  • ICD-10: Q87.8
  • OMIM: 256520  616038
  • UMLS: C0265218
  • MeSH: C536405
  • GARD: 102
  • MedDRA: -

Detailed information


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