Orphanet: Myoclonus dystonia syndrome

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Myoclonus-dystonia syndrome

Disease definition

Myoclonus-dystonia syndrome (MDS) is a rare movement disorder characterized by mild to moderate dystonia along with 'lightning-like' myoclonic jerks.


Classification level: Disorder
  • Synonym(s):
    • Alcohol-responsive dystonia
    • Hereditary essential myoclonus
    • Myoclonic dystonia
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Autosomal dominant or Not applicable 
  • Age of onset: Childhood, Adolescent, Adult
  • ICD-10: G24.1
  • OMIM: 159900  616398
  • UMLS: C1834570
  • MeSH: C536096
  • GARD: 7139
  • MedDRA: -

Detailed information


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