Orphanet: Moebius syndrome

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Moebius syndrome

Disease definition

A very rare congenital cranial dysinnervation disorder characterized by complete or incomplete facial paralysis in association with bilateral palsy of the abducens nerve causing impairment of ocular abduction. The syndrome also includes various other congenital anomalies.


Classification level: Disorder
  • Synonym(s):
    • Congenital facial diplegia
    • Möbius syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant 
  • Age of onset: Neonatal
  • ICD-10: Q87.0
  • OMIM: 157900
  • UMLS: C0221060  C0853240
  • MeSH: D020331
  • GARD: 8549
  • MedDRA: 10030069

Detailed information

Article for general public


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