Orphanet: Cerebral autosomal recessive arteriopathy subcortical infarcts leukoencephalopathy

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy

Disease definition

CARASIL is a hereditary cerebral small vessel disease characterized by early-onset gait disturbances, premature scalp alopecia, ischemic stroke, acute mid to lower back pain and progressive cognitive disturbances leading to severe dementia.


Classification level: Disorder
  • Synonym(s):
    • Maeda syndrome
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive 
  • Age of onset: Adolescent, Adult
  • ICD-10: F01.1
  • OMIM: 600142
  • UMLS: C1838577
  • MeSH: -
  • GARD: 10424
  • MedDRA: -

Detailed information


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.