Orphanet: Generalized pustular psoriasis

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Generalized pustular psoriasis

Disease definition

Generalized pustular psoriasis is a severe inflammatory skin disease that can be life-threatening and that is characterized by recurrent episodes of high fever, fatigue, episodic erythematous cutaneous eruptions with sterile cutaneous pustules formation on various parts of the body, and neutrophil leukocytosis.


Classification level: Disorder
  • Synonym(s):
    • GPP
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Autosomal recessive or Not applicable 
  • Age of onset: Adult
  • ICD-10: L40.1
  • OMIM: 614204  616106
  • UMLS: C0343055
  • MeSH: -
  • GARD: 12819
  • MedDRA: -

Detailed information


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