Orphanet: Melorheostosis

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Disease definition

Melorheostosis is a rare connective tissue disorder characterized by a sclerosing bone dysplasia, usually limited to one side of the body (rarely bilateral), that manifests with pain, stiffness, joint contractures and deformities.


Classification level: Disorder
  • Synonym(s): -
  • Prevalence: <1 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: M85.8
  • OMIM: 155950
  • UMLS: C0025239
  • MeSH: D008557
  • GARD: 9474
  • MedDRA: 10050284

Detailed information

Article for general public


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