Orphanet: Lambert Eaton myasthenic syndrome

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Lambert-Eaton myasthenic syndrome

Disease definition

Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune, presynaptic disorder of neuromuscular transmission characterized by fluctuating muscle weakness and autonomic dysfunction frequently associated with small-cell lung cancer (SCLC).


Classification level: Disorder
  • Synonym(s): -
  • Prevalence: 1-9 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: G73.1
  • OMIM: -
  • UMLS: C0022972
  • MeSH: D015624
  • GARD: 6851
  • MedDRA: 10067685

Detailed information

Article for general public

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