Orphanet: Brugada syndrome

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Brugada syndrome

Disease definition

Brugada syndrome (BrS) manifests with ST segment elevation in right precordial leads (V1 to V3), incomplete or complete right bundle branch block, and susceptibility to ventricular tachyarrhythmia and sudden death. BrS is an electrical disorder without overt myocardial abnormalities.


Classification level: Disorder
  • Synonym(s):
    • Bangungut
    • Dream disease
    • Idiopathic ventricular fibrillation, Brugada type
    • Pokkuri death syndrome
    • SUNDS
    • Sudden unexplained nocturnal death syndrome
  • Prevalence: 1-5 / 10 000
  • Inheritance: Autosomal dominant or Not applicable 
  • Age of onset: Adult, Childhood
  • ICD-10: I49.8
  • OMIM: 601144  611777  611875  611876  612838  613119  613120  613123  616399
  • UMLS: C1142166  C1955837
  • MeSH: D053840
  • GARD: 1030
  • MedDRA: 10059027

Detailed information


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