Orphanet: Bacterial susceptibility due to TLR signaling pathway deficiency

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Bacterial susceptibility due to TLR signaling pathway deficiency

Disease definition

Pyogenic bacterial infection due to MyD88 deficiency is a primary immunodeficiency characterized by increased susceptibility to pyogenic bacterial infections, including invasive pneumococcal, invasive staphylococcal and pseudomonas disease.


Classification level: Disorder
  • Synonym(s): -
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive 
  • Age of onset: Childhood
  • ICD-10: D84.8
  • OMIM: 612260
  • UMLS: C2677092
  • MeSH: -
  • GARD: 12638
  • MedDRA: -
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