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ADAM17 - ADAM metallopeptidase domain 17
- Synonym(s) : a disintegrin and metalloproteinase 17, cartilage snake venom-like protease, CD156B, cSVP, TNF-alpha convertase enzyme
- Previous symbols and names : 'tumor necrosis factor, alpha, converting enzyme', TACE, Tumor necrosis factor, alpha, converting enzyme
- Type : gene with protein product
- Chromosomal location : 2p25.1
- OMIM: 603639
- HGNC: 195
- UniProtKB: P78536
- Genatlas: ADAM17
- GenCC: ADAM17
- Ensembl: ENSG00000151694
- IUPHAR-DB: 1662
- Reactome: P78536
- LOVD: ADAM17
Diseases list
- Disease-causing germline mutation(s) (loss of function) in Neonatal inflammatory skin and bowel disease
ORPHA:294023 
: AssessedAdditional information
Patient-centred resources for this gene
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