Orphanet: Essential thrombocythemia

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Essential thrombocythemia

Disease definition

Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN, see this term) characterized by a sustained elevation of platelet number (> 450 x 109/L) with a tendency for thrombosis and hemorrhage.


Classification level: Disorder
  • Synonym(s):
    • ET
    • Essential thrombocytosis
  • Prevalence: 1-5 / 10 000
  • Inheritance: Multigenic/multifactorial or Not applicable 
  • Age of onset: All ages
  • ICD-10: D47.3
  • OMIM: 187950  601977  614521
  • UMLS: C0040028
  • MeSH: D013920
  • GARD: 6594
  • MedDRA: 10015493

Detailed information

Article for general public


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