Orphanet: Hereditary late onset Parkinson disease

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Hereditary late-onset Parkinson disease

Disease definition

Hereditary late-onset Parkinson disease (LOPD) is a form of Parkinson disease (PD), characterized by an age of onset of more than 50 years, tremor at rest, gait complaints and falls, bradykinesia, rigidity and painful cramps. Patients usually present a low risk of developing non motor symptoms, dystonia, dyskinesia and levodopa-induced dyskinesia (LID).


Classification level: Disorder
  • Synonym(s):
    • Autosomal dominant late-onset Parkinson disease
    • LOPD
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant 
  • Age of onset: Adult, Elderly
  • ICD-10: G20
  • OMIM: 168601  605543  607060  607688  614203  614251  616361
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information


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