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Ito hypomelanosis

Disease definition

Hypomelanosis of Ito (HI) is a multisystemic neurocutaneous condition with hypopigmented skin lesions along the Blaschko lines.


  • Synonym(s):
    • HI syndrome
    • Hypomelanosis of Ito
    • Incontinentia pigmenti type 1
    • Pigmentary mosaicism, Ito type
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant or Autosomal recessive or X-linked recessive or Not applicable 
  • Age of onset: Childhood
  • ICD-10: Q87.8
  • OMIM: 300337
  • UMLS: C0022283
  • MeSH: -
  • GARD: 2992
  • MedDRA: -

Detailed information

Article for general public

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