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Rare cutaneous lupus erythematosus

Disease definition

Rare cutaneous lupus erythematosus (CLE) is an autoimmune disease that denotes a heterogeneous spectrum of clinical manifestations affecting the skin and can be divided into 4 categories: acute CLE (ACLE); subacute CLE (SCLE); chronic CLE (CCLE; the most diverse form); and intermittent CLE (ICLE). CLE can either occur alone or associated with systemic lupus erythematosus (SLE).

ORPHA:535

  • Synonym(s): -
  • Prevalence: 1-5 / 10 000
  • Inheritance: Multigenic/multifactorial 
  • Age of onset: All ages
  • ICD-10: L93.0  L93.1  L93.2
  • OMIM: -
  • UMLS: C0024137
  • MeSH: D008178
  • GARD: 6225
  • MedDRA: 10056509
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