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MELAS
Disease definition
MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke) syndrome is a rare progressive multisystemic disorder characterized by encephalomyopathy, lactic acidosis, and stroke-like episodes. Other features include endocrinopathy, heart disease, diabetes, hearing loss, and neurological and psychiatric manifestations.
ORPHA:550
- Synonym(s):
- Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes
- Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes
- Prevalence: 1-9 / 1 000 000
- Inheritance: Mitochondrial inheritance or Not applicable
- Age of onset: Adolescent, Adult, Childhood
- ICD-10: G71.3
- OMIM: 540000
- UMLS: C0162671
- MeSH: D017241
- GARD: 7009
- MedDRA: 10053872
Detailed information
Article for general public
Professionals
- Anesthesia guidelines
- English (2018, pdf)
- Clinical practice guidelines
- Deutsch (2012)
- Clinical genetics review
- English (2018)
Additional information
Further information on this disease
Health care resources for this disease
Research activities on this disease
Specialised Social Services
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.