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Continuous spikes and waves during sleep

Disease definition

Continuous spikes and waves during sleep (CSWS) is a rare epileptic encephalopathy of childhood characterized by seizures, an electroencephalographic (EEG) pattern of electrical status epilepticus in sleep (ESES) and neurocognitive regression in at least 2 domains of development.


Classification level: Disorder
  • Synonym(s):
    • CSWS
    • CSWSS syndrome
    • Continuous spikes and waves during slow-wave sleep
    • Epileptic encephalopathy with continuous spike-and-wave during slow sleep
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant or Not applicable 
  • Age of onset: Childhood
  • ICD-10: G40.4
  • ICD-11: 8A62.Y
  • OMIM: 245570
  • UMLS: C5552731
  • MeSH: -
  • GARD: -
  • MedDRA: 10078827

Detailed information


Disease review articles

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