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SAPHO syndrome

Disease definition

SAPHO syndrome (acronym for Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) is an auto-inflammatory disease, mainly characterized by the association of neutrophilic cutaneous involvement and chronic osteomyelitis.


  • Synonym(s):
    • Synovitis-acne-pustulosis-hyperostosis-osteitis syndrome
  • Prevalence: Unknown
  • Inheritance: Multigenic/multifactorial or Not applicable 
  • Age of onset: Adolescent, Childhood, Adult
  • ICD-10: M86.3
  • OMIM: -
  • UMLS: C0263859
  • MeSH: -
  • GARD: 7606
  • MedDRA: 10051316

Detailed information

Article for general public


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