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Van der Woude syndrome

Disease definition

Van der Woude syndrome (VWS) is a rare congenital genetic dysmorphic syndrome characterized by paramedian lower-lip fistulae, cleft lip with or without cleft palate, or isolated cleft palate.


Classification level: Disorder
  • Synonym(s):
    • Cleft lip/palate with mucous cysts of lower lip
    • Lip-pit syndrome
    • VWS
  • Prevalence: 1-9 / 100 000
  • Inheritance: Autosomal dominant or Not applicable 
  • Age of onset: Neonatal
  • ICD-10: Q38.0
  • OMIM: 119300  604547  606713
  • UMLS: C0175697
  • MeSH: C536528
  • GARD: 8414
  • MedDRA: -

Detailed information


The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.