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Zollinger-Ellison syndrome

Disease definition

Zollinger-Ellison syndrome (ZES) is characterized by severe peptic disease (ulcers/esophageal disease) caused by hypergastrinemia secondary to a gastrinoma resulting in increased gastric acid secretion.


  • Synonym(s):
    • Gastrinoma
  • Prevalence: 1-9 / 100 000
  • Inheritance: Not applicable 
  • Age of onset: Adult, Elderly
  • ICD-10: C25.4  D37.7  E16.4
  • OMIM: -
  • UMLS: C0017150  C0043515
  • MeSH: D015043  D015408
  • GARD: 7918
  • MedDRA: 10017852

Detailed information


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