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Chronic myelomonocytic leukemia

Disease definition

A rare myelodysplastic/myeloproliferative neoplasm characterized by a spectrum of clinical, hematological, and morphological features, ranging from predominantly myelodysplastic to mainly myeloproliferative in nature, with blood monocytosis (> 1G/L, constituting > 10% of circulating leukocytes). Is it often associated with blood cytopenia and/or ''proliferative features'' (increased leukocyte counts, splenomegaly), with marrow dysplasia and risk of progression to acute myeloid leukemia (AML).


Classification level: Disorder
  • Synonym(s):
    • CMML
  • Prevalence: -
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: C93.1
  • ICD-11: 2A40
  • OMIM: -
  • UMLS: C0023480
  • MeSH: D015477
  • GARD: 8225
  • MedDRA: 10009018

Detailed information


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