Orphanet: Chronic beryllium disease

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Chronic beryllium disease

Disease definition

A pneumoconiosis, characterized by granulomatous inflammation, that occurs in individuals who develop beryllium sensitization (BeS), a cell-mediated immune response to environmental and occupational beryllium exposure. BeS precedes the lung disease that may present with chronic dry cough, fatigue, weight loss, chest pain, and increasing dyspnea.


Classification level: Disorder
  • Synonym(s):
    • Berylliosis
    • Chronic berylliosis
    • Chronic beryllium lung disease
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: J63.2
  • OMIM: -
  • UMLS: C0005138  C0221052
  • MeSH: D001607
  • GARD: 867
  • MedDRA: 10004485

Detailed information


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