Orphanet: Neurotrophic keratopathy

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Neurotrophic keratopathy

Disease definition

Neurotrophic keratopathy is a rare degenerative disease of the cornea characterized by reduction or loss of corneal sensitivity that can be asymptomatic or present with red-eye and, during the early stages of the disease, a minor decrease in visual acuity. It eventually leads to loss of vision.


Classification level: Disorder
  • Synonym(s):
    • Neurotrophic keratitis
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: Childhood, Adult
  • ICD-10: H16.2
  • OMIM: -
  • UMLS: C0339296
  • MeSH: -
  • GARD: -
  • MedDRA: 10069732
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