Orphanet: Catel Manzke syndrome

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Catel-Manzke syndrome

Disease definition

Catel-Manzke syndrome is a rare bone disease characterized by bilateral hyperphalangy and clinodactyly of the index finger typically in association with Pierre Robin sequence (see this term) comprising micrognathia, cleft palate and glossoptosis.


Classification level: Disorder
  • Synonym(s):
    • Hyperphalangy-clinodactyly of index finger with Pierre Robin syndrome
    • Index finger anomaly-Pierre Robin syndrome
    • Micrognathia digital syndrome
    • Palatodigital syndrome, Catel-Manzke type
    • Pierre Robin sequence-hyperphalangy-clinodactyly syndrome
    • Pierre Robin syndrome-hyperphalangy-clinodactyly syndrome
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal recessive 
  • Age of onset: Neonatal
  • ICD-10: Q87.8
  • OMIM: 302380  616145
  • UMLS: C1844887
  • MeSH: C535347
  • GARD: 28
  • MedDRA: -

Detailed information


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