Orphanet: Cleft lip/palate

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Cleft lip/palate

Disease definition

Cleft lip and palate is a fissure type embryopathy extending across the upper lip, nasal base, alveolar ridge and the hard and soft palate.


Classification level: Disorder
  • Synonym(s):
    • Alveolar cleft lip and palate
    • Cleft lip and palate
    • Cleft lip-alveolus-palate syndrome
    • FLP
  • Prevalence: 1-5 / 10 000
  • Inheritance: Multigenic/multifactorial 
  • Age of onset: Infancy, Neonatal
  • ICD-10: Q37.0  Q37.1  Q37.2  Q37.3  Q37.4  Q37.5  Q37.8  Q37.9
  • OMIM: 119530  129400  225060  600625  600757  602966  608371  608864  608874  610361  612858  613705  616788  618149
  • UMLS: C0158646
  • MeSH: -
  • GARD: -
  • MedDRA: 10009260

Detailed information


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