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Axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy
Disease definition
A rare acquired peripheral neuropathy characterized by symmetric, slowly progressive, predominantly sensory neuropathy, mostly limited to the legs with numbness and paresthesia of the distal leg and mild imbalance. Some patients may experience pain, weakness of foot dorsiflexion, mild proximal leg weakness, and/or upper limb involvement. The majority of patients have IgG monoclonal gammopathy. Systemic illnesses are absent in most cases.
ORPHA:209004
Classification level: Disorder- Synonym(s): -
- Prevalence: Unknown
- Inheritance: Not applicable
- Age of onset: Adult, Elderly
- ICD-10: G61.8
- OMIM: -
- UMLS: C5680822
- MeSH: -
- GARD: -
- MedDRA: -
A summary on this disease is available in Español (2023) Nederlands (2023)
Detailed information
General public
- Article for general public
- Svenska (2022) - Socialstyrelsen
Guidelines
- Clinical practice guidelines
- Deutsch (2012) - AWMF


Additional information
Further information on this disease
Patient-centred resources for this disease
Research activities on this disease
Specialised Social Services
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